First Place: Robert Pagels, Chemical and Biological Engineering – Sustained Delivery of Biologics with IFNP
We have recently developed and patented Inverted Flash NanoPrecipitation (IFNP), a technology capable of producing microparticles highly loaded with biologically-derived drugs. These drugs are the most rapidly growing segment of the pharmaceutical marketplace, and their share is expected to surpass $200 billion by 2019. However, they must be administered by frequent injections, resulting in patient discomfort and poor adherence. Our process generates microparticles which release the biologic slowly over time, and could decrease the frequency of injection from daily to monthly or even biannually. IFNP is an industrially scalable and economical route to microparticles, making it of interest to leading pharmaceutical companies.
Second Place: Niraj Jha, Electrical Engineering – Smart, Secure, Yet Energy-Efficient, IOT Senors
Internet-of-Things (IoT) is expected to have a $3-6 trillion impact per year by 2025. Unfortunately, IoT currently has an Achilles heel: security. The security attacks on IoT can be mitigated through the use of cryptographic techniques in IoT sensors. However, such techniques are currently not employed because of their significant energy overhead. We provide a way out of this predicament through inference and cryptography. This dramatically reduces communication energy, which dominates the energy consumption of IoT sensors. We expect this technology to have an impact across the IoT spectrum.
Third Place: Yuyang Fan, Mechanical and Aerospace Engineering - Real-Time Monitoring of Medical Injections
Errors associated with incorrect drug administration are common, costly, and dangerous. Real-time monitoring of the injection flow rate into a patient would be ideal, but due to technical limitations is currently impossible. Using a novel technique, called Elastic Filament Velocimetry (EFV), we have designed a sensor architecture able to monitor even the most minute flow rates associated with medical infusion. Utilizing modern MEMS manufacturing techniques, these sensors can be inexpensively manufactured and are ideal for use with disposable tube sets and other injection applications.
Tendo Technologies will commercialize the unique sensor platform that will revolutionize medical infusions.